
Charged Aerosol Detectors
Corona Veo and Corona Veo RS
Operating Instructions Page 15
2 Overview
2.1 Unit Description
The detector is a modern high-quality instrument designed for HPLC, UHPLC and
microLC analyses, especially as part of the UltiMate 3000 system.
• The detector uses charged aerosol detection (CAD) technology for liquid
chromatography. This technique enables detection of all non-volatile and many semi-
volatile analytes in the eluent.
• The compound that is analyzed does not need to possess a chromophore as is the case
with UV detection. Also, the compound does not need to be ionized as is the case with
mass spectrometry.
• The detector provides great sensitivity and a wide dynamic range. Under isocratic
conditions, non-volatile analytes produce similar response, independent of chemical
structure.
• Fast data sampling ensures full compatibility with HPLC and UHPLC applications.
• The concentric design of the FocusJet™ nebulizer provides an extended flow rate range.
In addition, the adjustable evaporation temperature optimizes analyte response.
• Controlling the detector by the Chromeleon Chromatography Management System
provides a high degree of system integration, as well as maximum analysis efficiency due
to comprehensive data analysis and evaluation features in Chromeleon.
• All parts that may be exposed to solvents are made of materials that provide optimum
resistance to the most commonly used solvents and buffer solutions in HPLC.
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