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Charged Aerosol Detectors
Corona Veo and Corona Veo RS
Operating Instructions Page 15
2 Overview
2.1 Unit Description
The detector is a modern high-quality instrument designed for HPLC, UHPLC and
microLC analyses, especially as part of the UltiMate 3000 system.
The detector uses charged aerosol detection (CAD) technology for liquid
chromatography. This technique enables detection of all non-volatile and many semi-
volatile analytes in the eluent.
The compound that is analyzed does not need to possess a chromophore as is the case
with UV detection. Also, the compound does not need to be ionized as is the case with
mass spectrometry.
The detector provides great sensitivity and a wide dynamic range. Under isocratic
conditions, non-volatile analytes produce similar response, independent of chemical
structure.
Fast data sampling ensures full compatibility with HPLC and UHPLC applications.
The concentric design of the FocusJet™ nebulizer provides an extended flow rate range.
In addition, the adjustable evaporation temperature optimizes analyte response.
Controlling the detector by the Chromeleon Chromatography Management System
provides a high degree of system integration, as well as maximum analysis efficiency due
to comprehensive data analysis and evaluation features in Chromeleon.
All parts that may be exposed to solvents are made of materials that provide optimum
resistance to the most commonly used solvents and buffer solutions in HPLC.
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